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You can fly and/or drive to Page Lake Powell. There are no buses, such as Greyhound, that go between Flagstaff or Phoenix and Page Lake Powell.
The Page Municipal Airport has an Avis Car Rental, and Flagstaff and Phoenix airports have a plethora of car rental options.
Tap on headings for more info
From St George, UT:
Route: Via US-89 Drive Time: Approx. 2 hrs. 40 min. Distance: 154 miles.
Route: Via US-89 S Drive Time: Approx. 2 hrs. 14 min. Distance: 129 miles.
From Phoenix, AZ:
Route: Via US-89 S and I-17 S Drive Time: Approx. 4 hrs. 14 min. Distance: 272 miles.
From St George Regional Airport:
Flight Time: St. George to Phoenix approx. 1 hr. 18 min.
Flight Time: Phoenix to Page approx. 1 hr. 12 min.
From Flagstaff Pulliam Airport:
Flight Time: Flagstaff to Phoenix Approx. 54 min.
Flight Time: Phoenix to Page Approx. 1 hr. 12 min.
From Phoenix Sky Harbor International Airport:
Flight Time: Approx. 1 hrs. 12 min.
You can take a taxi to your destination or, depending on where you're staying, there may be a shuttle service available (ask your hotel).